Phosphatidylserine (PS) is a phospholipid that is a key component of cell membranes, particularly concentrated in the brain. It is one of very few supplements with an FDA-qualified health claim, stating that it "may reduce the risk of cognitive dysfunction in the elderly." Clinical studies have shown benefits for memory, attention, and processing speed in older adults. In athletes, phosphatidylserine has been studied for its ability to blunt cortisol response during intense training. Modern supplements are derived from soy or sunflower lecithin (earlier products used bovine brain). Typical doses range from 100–300mg per day. Products below are ranked by cost at your chosen daily dose.
Read our Phosphatidylserine price comparison guide for tips on what to look for when buying phosphatidylserine.
| # | Product | 30-day cost | Supply | Sticker | |
|---|---|---|---|---|---|
| 1 |
BulkSupplements.com Phosphatidylserine Capsules - Phosphatidylserine Supplement - Gluten Free, 1 Capsule per Serving (60mg), 240 Capsules (Pack of 1)
BulkSupplements Store
|
$3.12 | 48d | $24.97 | View on Amazon |
| 2 |
Phosphatidylserine Supplement, 400mg Serving, 240 Capsules – Soy Free Sunflower Lecithin Source
DEAL SUPPLEMENT Store
|
$6.24 | 32d | $24.95 | View on Amazon |
| 3 |
ML Naturals Phosphatidyl Serine 200mg (Per Serving) – 120 Vegetable Capsules – Non-GMO – Supports Memory & Brain Function
ML Naturals Store
|
$7.49 | 40d | $14.99 | View on Amazon |
| 4 |
Doctor's Best Phosphatidylserine Supplement 100 mg - Phosphatidyl Serine Capsules for Men & Women, Memory & Cognitive Support for Adults, Supports Brain Health, Gluten Free, Vegan - 120 Veg Caps
Doctor's BEST Store
|
$7.50 | 40d | $29.99 | View on Amazon |
| 5 |
Life Extension PS Caps, phosphatidylserine, for Cognitive Performance, Gluten-Free, Non-GMO, Vegetarian, 100 Capsules
Life Extension Store
|
$8.00 | 33d | $26.67 | View on Amazon |
| 6 |
BESTVITE Phosphatidylserine 100mg per Capsule (120 Vegetarian Capsules) with Sharp-PS® Green - Patented and Clinically Tested - Stearate Free - Soy Free - Gluten Free - Vegan - Non GMO
BESTVITE Store
|
$8.25 | 40d | $32.99 | View on Amazon |
| 7 |
Phosphatidylserine 400 mg – Sunflower Phosphatidylserine Supplement – 120 Capsules (60 Servings) – PS Supplement for Brain, Memory & Cognitive Support – Non-GMO, ISO-Certified
Leaping Lynx Store
|
$8.97 | 80d | $17.94 | View on Amazon |
| 8 |
Phosphatidylserine Pure 500mg – 180 Vegetarian Pills, 3-Month Supply, Supplement for Strengthening Memory, Focus & Cognitive Function, Made in USA, Lab Tested, Non GMO
LongLifeNutri Store
|
$9.00 | 30d | $26.99 | View on Amazon |
| 9 |
NOW Foods Supplements, Phosphatidyl Serine 100 mg with Phospholipid compound derived from Soy Lecithin, 120 Veg Capsules
NOW Foods Store
|
$9.39 | 40d | $37.55 | View on Amazon |
| 10 |
Swanson Phosphatidylserine 100 mg 90 Sgels (2 Pack)
Swanson Ultra
|
$9.52 | 60d | $57.09 | View on Amazon |
| 11 |
Intelligent Labs Phosphatidylserine Supplement 100mg, 90 High Strength Capsules, 100% Soy and Allergen-Free, Pure Phosphatidylserine from Sunflower Lecithin
Intelligent Labs Store
|
$9.66 | 15d | $28.99 | View on Amazon |
| 12 |
Phosphatidylserine Supplement 300mg per Serving Memory and Focus Support PS Brain Supplement for Adults Cognitive Health 60 Capsules 2 Daily 30 Day Supply
TrySafe
|
$9.99 | 30d | $9.99 | View on Amazon |
| 13 |
NOW Foods Supplements, Phosphatidyl Serine 100 mg with Phospholipid compound derived from Soy Lecithin, 60 Veg Capsules
NOW Foods Store
|
$10.00 | 20d | $19.99 | View on Amazon |
| 14 |
Swanson Phosphatidylserine 100 Milligrams 90 Sgels
Swanson Store
|
$10.06 | 30d | $30.19 | View on Amazon |
| 15 |
NatureBell Phosphatidylserine 500mg - 240 Capsules - Brain Health Support for Men & Women* - Bioavailable Sunflower Lecithin - Easy-to-Swallow Supplement - Gluten-Free
NatureBell Store
|
$10.12 | 27d | $26.99 | View on Amazon |
| 16 |
PhosphatidylSerine Supplement 300mg Per Serving, 120 Capsules (Phosphatidyl Serine Complex) by Double Wood
Double Wood Supplements Store
|
$10.48 | 12d | $20.95 | View on Amazon |
| 17 |
Source Naturals Phosphatidyl Serine Complex Stablilized Enzyme Supplement 500mg - 100% Pure - 60 Softgels
Source Naturals Store
|
$10.97 | 20d | $21.95 | View on Amazon |
| 18 |
Choline Gummies for Kids & Adults, Choline Supplements 500mg with DHA, Phosphatidylserine for Brain Health, Focus, Immune Support, Sugar-Free, Vegan, Strawberry Flavor, 60 Gummies
NATISLAND Store
|
$11.00 | 16d | $21.99 | View on Amazon |
| 19 |
Source Naturals Phosphatidyl Serine Matrix 500mg - 60 Softgels
Source Naturals Store
|
$11.20 | 20d | $22.40 | View on Amazon |
| 20 |
PhosphatidylSerine Nootropics Brain Support Supplement - Evlution Nutrition Phosphatidylserine 300mg per Serving Brain Supplement for Memory and Focus Support - Vegan and Non-GMO (30 Servings)
Evlution Store
|
$11.99 | 6d | $11.99 | View on Amazon |
| 21 |
Nature's Way Phosphatidylserine, Supports Brain Function*, 100 mg per Serving, 60 Softgels (Packaging May Vary)
Nature's Way Store
|
$12.03 | 20d | $24.06 | View on Amazon |
| 22 |
Natural Factors, Phosphatidylserine, Support for Memory, Concentration and Brain Functions, Soy and Gluten Free, 120 Softgels
Natural Factors Store
|
$12.59 | 40d | $50.37 | View on Amazon |
| 23 |
Jarrow Formulas PS100 Phosphatidylserine 100mg, Dietary Supplement for Brain Health and Cognitive Function Support, 120 Softgels, Up to a 40-120 Day Supply
Jarrow Formulas Store
|
$13.44 | 40d | $53.77 | View on Amazon |
| 24 |
Swanson Phosphatidylserine 100 Milligrams 30 Sgels
Swanson Store
|
$13.49 | 10d | $13.49 | View on Amazon |
| 25 |
NOW Foods Supplements, Soy-Free Phosphatidyl Serine (150mg), Brain Health*, 60 Veg Capsules
NOW Foods Store
|
$13.65 | 30d | $27.30 | View on Amazon |
| 26 |
Number One Nutrition Premium Phosphatidylserine 400mg, Derived from Sunflower Lecithin to Help Support Memory, Focus & Cognition Naturally, Soy Free, 120 Veg Caps
Number One Nutrition Store
|
$13.97 | 40d | $27.95 | View on Amazon |
| 27 |
Natural Factors, Phosphatidylserine, Support for Memory, Concentration and Brain Functions, Soy and Gluten Free, 60 Softgels
Natural Factors Store
|
$13.99 | 20d | $27.97 | View on Amazon |
| 28 |
Natural Factors, Phosphatidylserine, Support for Memory, Concentration and Brain Functions, Soy and Gluten Free, 30 Softgels
Natural Factors Store
|
$14.67 | 10d | $14.67 | View on Amazon |
| 29 |
Soy Free Phosphatidylserine 100mg - Phosphatidylserine Supplement from Sunflower Lecithin, Patented Sharp PS100, Brain Health, Memory Aid, Cortisol Control, Mental Sharpness, Non GMO, 90 Softgels
Natural BioScience Store
|
$14.98 | 30d | $44.95 | View on Amazon |
| 30 |
Phosphatidylserine 600 mg with L-Carnosine 500 mg + B6, B12 & Folate — Non-Soy Sunflower Lecithin PS Complex — Plant-Based, Non-GMO — Supports Cognitive Function, Cell Membrane Integrity — 60 Capsules
WONDER FAMILY Store
|
$14.99 | 60d | $14.99 | View on Amazon |
| 31 |
Jarrow Formulas PS100 Phosphatidylserine 100mg, Dietary Supplement for Brain Health and Cognitive Function Support, 120 Capsules, Up to a 120 Day Supply
Jarrow Formulas Store
|
$15.25 | 40d | $60.99 | View on Amazon |
| 32 |
Source Naturals Phosphatidyl Serine Matrix 500 mg - 30 Softgels
Source Naturals Store
|
$15.73 | 10d | $15.73 | View on Amazon |
| 33 |
Brain Supplements Gummies - 3X Strength Brain Gummy Vitamin Plus Nootropics For Memory, Focus, Concentration - Phosphatidylserine, B6, B12 & Nootropic, Clarity Support Supplement - 60 Gummies
Nature's Nutrition Store
|
$15.82 | 5d | $15.82 | View on Amazon |
| 34 |
Toniiq Phosphatidylserine - 400mg Formula - World’s First 50% Purity - Highest Purity in the US - Soy Free Phosphatidylserine Supplement - 90 Veggie Capsules
Toniiq
|
$16.17 | 30d | $24.26 | View on Amazon |
| 35 |
BoostCeuticals Phosphatidylserine 100mg with Ginkgo DMAE Gotu Kola - Memory, Stress & Cortisol Support, Cognitive Focus, Sleep Health, Brain Function Supplement, 90 Capsules
BoostCeuticals Store
|
$16.57 | 15d | $24.85 | View on Amazon |
| 36 |
Phosphatidylserine Supplement 100mg, Focus Gummies for Kids Teens + Vitamin C & D3 400IU, Sugar Free Kids Brain Gummies Increase Attention & Concentration, Chewable, Vegan, Gluten Free, Non-GMO 2 Pack
Nextdia Store
|
$16.64 | 20d | $33.29 | View on Amazon |
| 37 |
Soy Free Phosphatidylserine 100mg Softgel - PS Supplement Boosts Memory, Focus, Problem Solving, Cortisol Control. Natural Sunflower Lecithin, Patented Sharp PS-Green. Non-GMO, 60 Softgels
Natural BioScience Store
|
$17.48 | 20d | $34.95 | View on Amazon |
| 38 |
Brain Supplements for Memory and Focus with Phosphatidylserine, Nootropic Memory Supplement Gummy for Brain Health, Concentration, Mental & Cognitive Support, Focus Vitamins with B6 & B12-60 Gummies
Nature's Nutrition Store
|
$17.82 | 5d | $17.82 | View on Amazon |
| 39 |
Country Life Sharp Thought - Memory & Cognitive Support Supplement – Sharp-PS Gold Phosphatidylserine + DHA – Promotes Mental Clarity & Faster Recall – Gluten-Free, 60 Capsules
Country Life Store
|
$19.67 | 20d | $39.33 | View on Amazon |
| 40 |
Nootropic Brain Booster Gummies Supplement - Memory, Focus & Concentration Gummy with Vitamins B6 & B12, Proven and Tested Phosphatidylserine - Natural Cognitive Function & Energy Boost, 60 Gummies
Built by Nature Store
|
$19.82 | 5d | $19.82 | View on Amazon |
| 41 |
Brain Supplements for Memory & Focus Gummies - Brain Health Clarity with B6 B12 & Phosphatidylserine - Natural Nootropics Cognitive Concentration & Alertness Support Vitamins - 60 Vegan Gummies
Nature's Nutrition Store
|
$19.82 | 5d | $19.82 | View on Amazon |
| 42 |
Phosphatidylserine Supplement 100mg, Focus Gummies for Kids Teens + Vitamin C & D3 400IU, Sugar Free Kids Brain Gummies Increase Attention & Concentration, Chewable, Vegan, Gluten Free, Non-GMO 60Cts
Nextdia Store
|
$20.99 | 10d | $20.99 | View on Amazon |
| 43 |
Klaire Labs SFI Health Phosphatidyl Serine Sf - Cognitive Support, Soy Free Phosphatidylserine from Sunflower Lecithin (60 Capsules)
SFI Health Store
|
$22.00 | 20d | $43.99 | View on Amazon |
| 44 |
Solgar Phosphatidyl-Serine 200 mg, 60 Softgels - Premium Brain Health Supplement, Supports a Healthy Mind & Cognitive Function - Gluten Free, Dairy Free - 60 Servings
Solgar Store
|
$22.22 | 40d | $44.44 | View on Amazon |
| 45 |
NOW Supplements, Phosphatidyl Serine 300 mg, Extra Strength, with Phospholipid compound derived from Soy Lecithin, 50 Softgels
NOW Foods Store
|
$22.58 | 50d | $37.64 | View on Amazon |
| 46 |
Carlson - Phosphatidyl Serine, 100 mg, Non-GMO, Brain Function, 90 Softgels
Carlson Store
|
$23.49 | 30d | $70.47 | View on Amazon |
| 47 |
Nutricost Phosphatidylserine 400mg, 120 Capsules - Soy Free, 30 Servings, Vegetarian Friendly, Non-GMO, Gluten Free
Nutricost Store
|
$23.95 | 40d | $23.95 | View on Amazon |
| 48 |
2 Pack Algae Omega 3 Gummies for Adults, Plant Based DHA 460mg & EPA 230mg, Omega 3 Fish Oil Alternative for Adults, Plus MethylFolate, Vitamin B12, Phosphatidylserine, No Fishy Taste, Sugar Free
NEVISS Store
|
$24.40 | 20d | $48.79 | View on Amazon |
| 49 |
Seeking Health Phosphatidyl Serine - Brain Support Supplement with Sunflower Oil & Phospholipids - Vegetarian & Gluten-Free Capsules - 150 mg, 60 Capsules
Seeking Health Store
|
$24.50 | 30d | $49.00 | View on Amazon |
| 50 |
Integrative Therapeutics Phosphatidylserine - Brain & Cognitive Function Support* - Supports Healthy Stress Response* - Soy-Free, Gluten-Free & Dairy-Free - 60 Softgels (60 Servings)
Integrative Therapeutics Store
|
$24.62 | 20d | $49.25 | View on Amazon |
| 51 |
Ayush Herbs AyuPhos - Phosphatidylserine Supplement for Men & Women, Soy-Free Phosphatidyl Serine, Brain, Memory, & Cognitive Support for Adults, 200mg Per Pill - 45 Servings
Ayush Herbs Store
|
$25.33 | 18d | $38.00 | View on Amazon |
| 52 |
ANDREW LESSMAN PS 200 Phosphatidyl Serine 60 Capsules - Supports Mental Clarity, Positive Mood, Memory, Cognitive Function. Essential for Neurotransmitter Production and Release. No Additives
ANDREW LESSMAN Store
|
$27.45 | 40d | $54.90 | View on Amazon |
| 53 |
THORNE - Phosphatidylserine - Supports Healthy Brain Function, Memory & Focus - Helps Regulate Cortisol During Stress* - Third-Party Certified - Gluten-Free, Dairy-Free - 60 Capsules
THORNE Store
|
$31.92 | 20d | $63.84 | View on Amazon |
| 54 |
NEURIVA Original Brain Supplements for Memory and Focus, Clinically Tested Nootropics Phosphatidylserine and Neurofactor, Caffeine Free, 50ct Strawberry Gummies
NEURIVA Store
|
$33.92 | 8d | $28.27 | View on Amazon |
| 55 |
Pure Encapsulations PS 100 | Phosphatidylserine Amino Acid Supplement for Brain and Memory* | 120 Capsules
Pure Encapsulations Store
|
$35.87 | 40d | $143.50 | View on Amazon |
| 56 |
Multivitamin for Women Gummies for 40+ with Omega-3, Niacinamide, B-Complex, Lutein, Iron, Choline, Phosphatidylserine, Vitamin D3 for Skin, Hair, Energy, Immune, Bone - Vegan, Sugar Free, 120Cts
Lerinettia Store
|
$35.99 | 10d | $35.99 | View on Amazon |
| 57 |
Metagenics Phosphatidylserine - Brain Support Supplement* for Focus, Memory & Learning* - 150 mg Sunflower Lecithin-Derived Phosphatidylserine - Non-GMO, Soy Free, Gluten-Free - 60 Softgels
Metagenics Store
|
$38.48 | 30d | $76.95 | View on Amazon |
| 58 |
NEURIVA Plus Brain Supplements for Memory and Focus, Clinically Tested Nootropics Neurofactor and Phosphatidylserine with Vitamin B12, Vitamin B6, 50 Count Strawberry Gummies
NEURIVA Store
|
$40.33 | 8d | $33.61 | View on Amazon |
| 59 |
Pure Encapsulations PS 100 | Phosphatidylserine Amino Acid Supplement for Brain and Memory* | 60 Capsules
Pure Encapsulations Store
|
$40.50 | 20d | $81.00 | View on Amazon |
| 60 |
Nextdia Phosphatidylserine Gummies for Adults (1 Pack) + Phosphatidylserine Supplement for Kids (2 Pack)
Nextdia Store
|
$41.66 | 10d | $41.66 | View on Amazon |
| 61 |
FIRST DAY Teen Brain & Focus Supplement Gummies Ages 13–18 | Study & Concentration Support with Cognizin® Citicoline & Phosphatidylserine | Vegan, Non-GMO, Caffeine-Free | 30-Day Supply
FIRST DAY Store
|
$43.95 | 11d | $43.95 | View on Amazon |
| 62 |
FIRST DAY Kids Focus & Brain Supplement Gummies Ages 4+ | Attention & Calm Support with Cognizin® Citicoline & Phosphatidylserine | Organic, Vegan | 30-Day Supply
FIRST DAY Store
|
$43.96 | 10d | $43.96 | View on Amazon |
| 63 |
Designs for Health PS 150 Phosphatidylserine Capsules - 150mg Soy-Free Sunflower Lecithin-Sourced Phosphatidyl Serine Supplement - May Help Support Brain Health (60 Capsules)
Designs for Health Store
|
$44.99 | 30d | $89.99 | View on Amazon |
| 64 |
Nextdia Phosphatidylserine Supplement 100mg + Beet Root Gummies
Nextdia Store
|
$51.66 | 10d | $51.66 | View on Amazon |
| 65 |
Nextdia Bundle - Phosphatidylserine Gummies 120 Counts + Berberine Gummies 120 Counts
Nextdia Store
|
$52.66 | 6d | $52.66 | View on Amazon |
| 66 |
Vital Nutrients Phosphatidylserine - 150mg Phosphatidylserine Supplement - Powerful Nootropic for Attention, Memory, and Mental Focus Support* - Gluten, Dairy, Soy Free - Non-GMO - 60 Softgels
Vital Nutrients Store
|
$53.99 | 30d | $53.99 | View on Amazon |
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