Lion's mane (Hericium erinaceus) is a medicinal mushroom studied for its effects on cognitive function and nerve health. It contains compounds called hericenones and erinacines that stimulate nerve growth factor (NGF) production in animal studies. Clinical trials in older adults have shown improvements in cognitive function scores. Products vary significantly in formulation — some use fruiting body extract, others use mycelium grown on grain, and potency differs between standardized extracts and plain powder. Dual-extract products (water and alcohol extraction) aim to capture both water-soluble and fat-soluble bioactive compounds. Products below are ranked by cost at your chosen daily dose.
| # | Product | 30-day cost | Supply | Sticker | |
|---|---|---|---|---|---|
| 1 |
BulkSupplements.com Organic Lion's Mane Mushroom Extract Powder - Lions Mane Supplement Powder, Superfood for Well-Being - Vegan, 1g per Serving, 1kg (2.2 lbs) (Pack of 1)
BulkSupplements Store
|
$1.17 | 1000d | $38.97 | View on Amazon |
| 2 |
BulkSupplements.com Organic Lion's Mane Mushroom Extract Powder - Mushroom Supplement, Brain Supplement for Memory and Focus Support - Vegan, 1g per Serving, 500g (1.1 lbs) (Pack of 1)
BulkSupplements Store
|
$1.56 | 500d | $25.97 | View on Amazon |
| 3 |
Lion's Mane Mushroom Extract, 1 lb, Hericium Erinaceus Extract, Herbal Supplement, Always Pure
Jovvily Store
|
$1.88 | 454d | $24.49 | View on Amazon |
| 4 |
DEAL SUPPLEMENT Organic Lions Mane Mushroom Powder Supplement, 1,500mg Per Serving, 1lb – Active Fruiting Body & Mycelium Extract – Natural Brain Nootropic & Immune System Booster – Non-GMO
DEAL SUPPLEMENT
|
$2.18 | 453d | $21.99 | View on Amazon |
| 5 |
NatureBell Organic Lion’s Mane Powder 1,500mg - 1 lb - Brain, Focus & Memory Support* - Whole Fruiting Body & Mycelium - Non-GMO & Gluten-Free
NatureBell Store
|
$2.28 | 453d | $22.99 | View on Amazon |
| 6 |
PURE ORIGINAL INGREDIENTS Lion's Mane (730 Capsules) No Magnesium or Rice Fillers, Always Pure, Lab Verified
PURE ORIGINAL INGREDIENTS Store
|
$2.79 | 376d | $33.99 | View on Amazon |
| 7 |
Piping Rock Lions Mane Supplement | 180 Softgel Capsules | Mushroom Fruiting Body Extract | Non-GMO, Gluten Free
Piping Rock Store
|
$2.85 | 54d | $17.08 | View on Amazon |
| 8 |
Micro Ingredients Organic Lion’s Mane Mushroom Powder, 16oz | Pure Fruiting Body Superfood | Supports Brain, Focus, Energy & Immune Health | Great for Smoothies & Coffee | Filler Free, Vegan, Non-GMO
Micro Ingredients Store
|
$3.10 | 453d | $31.16 | View on Amazon |
| 9 |
Horbäach Lions Mane Supplement | 80 Absorbable Softgels | Non-GMO & Gluten Free Extract
Horbäach Store
|
$3.37 | 24d | $8.99 | View on Amazon |
| 10 |
10 in 1 High Strength Mushroom Supplement - Lions Mane, Cordyceps, Reishi - Brain Supplements for Memory and Focus ** 5-Month Supply
VEGATOT Store
|
$3.40 | 30d | $16.98 | View on Amazon |
| 11 |
Nutricost Mushroom Complex Supplement, 120 Capsules for 120 Servings per Bottle - 10 Mushroom Blend (Includes Reishi, Maitake, Shiitake, Lion's Mane, and More) - Non-GMO and Gluten Free
Nutricost Store
|
$3.49 | 6d | $13.95 | View on Amazon |
| 12 |
Micro Ingredients Ginkgo Biloba 120 mg Per Serving, 400 Softgels | 3-in-1 with Panax Ginseng & Lion’s Mane | Herbal Mushroom Blend | Made with MCT Oil | Non-GMO
Micro Ingredients Store
|
$3.60 | 10d | $23.99 | View on Amazon |
| 13 |
Nutricost Organic Lion's Mane Mushroom Powder 4oz - Certified USDA Organic
Nutricost Store
|
$3.70 | 113d | $13.95 | View on Amazon |
| 14 |
10 in 1 Lions Mane Mushroom Supplement with Turkey Tail, Reishi,Cordyceps, Chaga & More - Brain Supplements for Memory and Focus-150 Softgels
SIGNILIFE Store
|
$4.00 | 23d | $9.99 | View on Amazon |
| 15 |
10 in 1 Lions Mane Mushroom Supplement with Turkey Tail, Reishi,Cordyceps, Chaga & More - Brain Supplements for Memory and Focus-300 Softgels
SIGNILIFE Store
|
$4.00 | 45d | $19.99 | View on Amazon |
| 16 |
BulkSupplements.com Lion's Mane Mushroom Extract Capsules - Mushroom Supplement, Brain Supplement for Memory and Focus Support - Vegan, 2 Capsules per Serving (1000mg), 360 Capsules (Pack of 1)
BulkSupplements Store
|
$4.33 | 180d | $25.97 | View on Amazon |
| 17 |
Force Factor Lion’s Mane Supplement Capsules, Memory & Focus Supplement, Supports Nerve Health & Cognitive Function, Made with 100% Fruiting Body, Vegan, No Gelatin, Non-GMO, 60 Vegetable Capsules
Force Factor Store
|
$4.49 | 30d | $8.99 | View on Amazon |
| 18 |
Lions Mane Mushroom Supplement, 240* Capsules – Active Fruiting Body & Mycelium Extract – Natural Brain Nootropic & Immune System Booster – Non-GMO
DEAL SUPPLEMENT
|
$4.50 | 90d | $17.99 | View on Amazon |
| 19 |
Micro Ingredients Organic Lion’s Mane Mushroom Powder, 8oz | Pure Fruiting Body Superfood | Supports Brain, Focus, Energy & Immune Health | Great for Smoothies & Coffee | Filler Free, Vegan, Non-GMO
Micro Ingredients Store
|
$4.76 | 227d | $23.95 | View on Amazon |
| 20 |
NatureBell Lion’s Mane - 240 Capsules - Organic Fruiting Body & Mycelium - Brain, Immune & Energy Support* - High-Potency Extract - Non-GMO & Gluten-Free
NatureBell Store
|
$5.00 | 72d | $19.99 | View on Amazon |
| 21 |
FITO MEDIC'S Lab | Lions Mane Supplement Capsules | 120 Capsules | Mushroom Supplement
FITO MEDIC'S Store
|
$5.00 | 30d | $9.99 | View on Amazon |
| 22 |
ZEBORA Lions Mane Supplement Capsules - 5-in-1 Mushroom Supplement with Cordyceps, Reishi & Turkey Tail - Fruiting Body for Memory, Focus & Energy - 120 Vegan Capsules
ZEBORA Store
|
$5.00 | 36d | $9.99 | View on Amazon |
| 23 |
Wild & Organic Lions Mane Liquid Drops - Brain & Focus Support - Lion's Mane Mushroom Supplement - Hericium Erinaceus Mushroom Drops - Mix with Powder - Sugar & Alcohol-Free Extract Tincture - 4 oz
Wild & Organic Store
|
$5.18 | 113d | $28.99 | View on Amazon |
| 24 |
Micro Ingredients Lions Mane+ with Omega-3 EPA DHA & Phosphatidylserine – 240 Softgels with MCT Oil for Better Absorption – Fruiting Body & Mycelium Superfood Mushroom Extract – Lemon Flavored
Micro Ingredients Store
|
$5.50 | 60d | $21.99 | View on Amazon |
| 25 |
365 by Whole Foods Market, Lion's Mane Mushroom 500mcg, Vegan, 90 Count
365 by Whole Foods Market Store
|
$6.33 | 45d | $18.98 | View on Amazon |
| 26 |
Lions Mane Supplement, Liquid Mushroom Extract Drops, 8 Mushrooms Complex for Cognitive Support and Immunity Boost, Up to 2 Month Supply, Mushroom Supplement with Lion's Mane, Cordyceps, Reishi
Nature's live Store
|
$7.00 | 360d | $13.99 | View on Amazon |
| 27 |
Lions Mane Supplement Capsules - 120 Count - Mushroom Supplement, Brain Supplements for Memory and Focus, Lion's Mane Mushroom Capsules Organic - Cognitive and Immune Support, Focus Supplement
WELLNESS LABSRX Store
|
$7.49 | 90d | $14.99 | View on Amazon |
| 28 |
Micro Ingredients 10‑in‑1 Mega Mushroom Complex Supplement – Lions Mane, Cordyceps, Reishi, Chaga & More – 240 Softgels with MCT Oil – 4 Month Supply – Adaptogenic Functional Mushroom Blend
Micro Ingredients Store
|
$7.50 | 8d | $29.99 | View on Amazon |
| 29 |
Lions Mane Mushroom Gummies (60 Count) Focus Gummies & Brain Mushroom Supplement for Adults - Delicious Blueberry Flavor - Premium Lions Mane Supplement - Third Party Tested, Vegan Safe & USA Made
DORADO NUTRITION Store
|
$7.95 | 3d | $7.95 | View on Amazon |
| 30 |
DR. MORITZ Lions Mane Gummies for Adults and Kids 4+ - Mushroom Gummies with 12-in-1 Blend Including Reishi & Chaga - Lions Mane for Kids and Adults - No Sugar Added, Non-GMO (120 Count)
DR. MORITZ Store
|
$8.48 | 2d | $16.95 | View on Amazon |
| 31 |
Lions Mane Liquid - USDA Certified Organic Lions Mane Supplement - Brain Support, Energy, Memory & Focus - Sugar & Alcohol-Free Lion's Mane Mushroom Extract 72,000 mg / Bottle, 2 Fl OZ, 2 Month Supply
NUTRAHARMONY Store
|
$8.50 | 72d | $17.00 | View on Amazon |
| 32 |
Lions Mane Supplement Capsules - Organic Lions Mane - Made in USA - Fruiting Bodies Extract - 1200 mg, 25% Polysaccharides - Memory & Focus Support - As Lions Powder - 120 Capsules, 2 Month Supply
NUTRAHARMONY Store
|
$8.95 | 72d | $17.89 | View on Amazon |
| 33 |
Horbäach Lions Mane Mushroom Extract | 120 Capsules | Vegetarian, Non-GMO, Gluten Free Supplement
Horbäach Store
|
$8.99 | 252d | $17.99 | View on Amazon |
| 34 |
The Genius Brand Genius Lion's Mane - Plant-Based Supplement for Memory, Focus & Mood Support - Organic & Non-GMO - 120 Veggie Capsules
The Genius Brand Store
|
$9.26 | 72d | $18.51 | View on Amazon |
| 35 |
Fungies Lion's Mane Mushroom Gummies, Mixed Blueberry & Strawberry Flavor - Mushroom Supplement Gummy for Adults & Children Supports Brain Health, Cognitive Function, Focus, Memory & Mood, 60 Servings
Fungies Store
|
$9.77 | 30d | $19.55 | View on Amazon |
| 36 |
Earth Harmony Naturals Organic Lions Mane Supplement (1000mg), 2-Month Supply Lion's Mane Mushroom Supplement Extract to Support Focus, Memory (120 Capsules)
Earth Harmony Naturals Store
|
$9.98 | 60d | $19.95 | View on Amazon |
| 37 |
Lions Mane Mushroom Gummies for Nootropic Brain Supplement, Immune Support,Stress Relief Mushroom Supplement Berrry Flavor 60 Count
careleaf Store
|
$9.99 | 30d | $9.99 | View on Amazon |
| 38 |
Organic Lions Mane Mushroom Capsules (120 Count), for Focus Support and Immune Health, Third Party Tested and Grown in The USA - by Double Wood
Double Wood Supplements Store
|
$10.48 | 60d | $20.95 | View on Amazon |
| 39 |
Host Defense Lion's Mane Powder - Brain Health Support Supplement - Mushroom Supplement to Support Focus & Memory Function - Immune & Nervous System Support Supplement - 3.5 oz (66 Servings)*
Host Defense Store
|
$10.89 | 99d | $23.96 | View on Amazon |
| 40 |
Lions Mane Mushroom Gummies for Adults, 140 Count Bulk Lion's Mane Chewables, High Potency 10:1 Organic Extract amounts to 2000mg, Supplement Supports Mental Clarity, Focus, Mood and Brain Fog
HEALTHY HEIST Store
|
$11.12 | 14d | $25.95 | View on Amazon |
| 41 |
Nature's Truth Lion's Mane Gummies for Adults | 60 Count | Mixed Berry Flavor | Vegan, Non-GMO, & Gluten Free Supplement
Nature's Truth Store
|
$11.49 | 11d | $11.49 | View on Amazon |
| 42 |
Nature's Truth Lions Mane Mushroom Softgels | 30 Count | Extra Strength | Non GMO & Gluten Free Supplement
Nature's Truth Store
|
$11.49 | 9d | $11.49 | View on Amazon |
| 43 |
Lifeable Lions Mane Gummies for Adults | Great Tasting Lions Mane Mushroom Extract | Vegan, Kosher, Non-GMO Mushroom Gummies | Brain Support Supplement | 60 Count
Lifeable Store
|
$11.99 | 6d | $11.99 | View on Amazon |
| 44 |
Lion's Mane Supplement Capsules with Turkey Tail for Memory & Focus – 10:1 Mushroom Extract, Brain Fog Support, 1200mg, Third Party Tested, Non-GMO, Vegan, Made in USA, 120 Capsules, 2 Month Supply
Garden of Herbz Store
|
$12.50 | 60d | $24.99 | View on Amazon |
| 45 |
15in1 Mushroom Gummies with Lion's Mane Turkey Tail Cordyceps Reishi Chaga Sweet Toot Maitake Meshima Poria Cocos Shiitake Tremella, Oyster Agaricus Mushrooms for Men and Women Supplement Clean Nutra
Clean Nutraceuticals Store
|
$13.46 | 2d | $13.46 | View on Amazon |
| 46 |
Zazzee USDA Organic Lion's Mane 20:1 Extract, 1000 mg Per Serving, 30% Beta Glucans, 120 Vegan Capsules, Nootropic for Brain Health, Focus, Memory & Immune Support, All-Natural, Non-GMO, Made in USA
Zazzee Store
|
$13.99 | 60d | $27.97 | View on Amazon |
| 47 |
Gaia Herbs Lion's Mane Mushroom - Brain Health Support* - 120 Vegan Capsules (120 Servings)
Gaia Herbs Store
|
$14.17 | 54d | $56.69 | View on Amazon |
| 48 |
FreshCap Organic Mushroom Powder Supplement - Fruiting Body Extract (Lion's Mane, 60 Servings)
FreshCap Mushrooms Store
|
$14.99 | 60d | $29.99 | View on Amazon |
| 49 |
NOW Foods Supplements, Lion's Mane 500 mg, Super Mushroom, Made with Organic Lion's Mane Mushrooms, 60 Veg Capsules
NOW Foods Store
|
$15.10 | 30d | $15.10 | View on Amazon |
| 50 |
Nootropics Depot Lions Mane Mushroom Capsules | 8:1 Whole Fruiting Body Dual Extract | 500mg | 60 Count | Hericium erinaceus
Nootropics Depot Store
|
$16.49 | 30d | $32.99 | View on Amazon |
| 51 |
World's First Mushroom Complex Gummies with Lions Mane, Immune Support & Stress Relief, Nootropic Mushroom Supplement for Adults & Children (90 Chews 2500mg/serving)
Purify Life Store
|
$16.66 | 11d | $24.99 | View on Amazon |
| 52 |
Toniiq Lion’s Mane - Ultra High Potency 10:1 Extract with 30% Polysaccharides - Highly Concentrated & Bioactive - Third-Party Lab Tested - 120 Capsules
Toniiq
|
$19.48 | 72d | $25.97 | View on Amazon |
| 53 |
FreshCap Organic Mushroom Capsules Supplement - Fruiting Body Extract (Lion's Mane, 120 Capsules)
FreshCap Mushrooms Store
|
$20.00 | 60d | $39.99 | View on Amazon |
| 54 |
Sports Research® Organic Lion's Mane Mushroom Supplement 1800mg - Brain Health, Focus & Cognitive Supports - USDA Certified Organic · Non-GMO · Vegan - 90 Count Capsules
Sports Research Store
|
$21.56 | 54d | $21.56 | View on Amazon |
| 55 |
MaryRuth Organics Lions Mane Mushroom Supplement, Up to 1 Month Supply, Nootropic USDA Organic Lions Mane Extract Nervine Herbal Liquid Drops, Brain Health Non-GMO Vegan Alcohol Free Tincture, 1 Fl Oz
|
$21.90 | 35d | $21.90 | View on Amazon |
| 56 |
DR. EMIL NUTRITION 2100mg Organic Lions Mane Supplement Capsules - Focus, Mental Clarity & Cognition - Nootropic Lion's Mane Mushroom Supplement with Organic Lions Mane
DR. EMIL NUTRITION Store
|
$22.39 | 63d | $22.39 | View on Amazon |
| 57 |
Host Defense Mushrooms Lion's Mane Gummies - Brain Health Support - Mushroom Supplement to Support Focus & Memory Function - Immune & Nervous System Support - Blueberry, 90 Gummies*
Host Defense Store
|
$22.46 | 30d | $22.46 | View on Amazon |
| 58 |
Youtheory Lion's Mane+ Capsule 90 Vegetarian Capsules
Youtheory Store
|
$22.99 | 36d | $22.99 | View on Amazon |
| 59 |
Host Defense Mushrooms Lion's Mane - Supplement Capsules for Brain Health Support - Mushroom Support for Focus & Memory Function - Immune & Nervous System Supplement - 120 Capsules
Host Defense Store
|
$23.60 | 60d | $47.21 | View on Amazon |
| 60 |
Host Defense MycoBotanicals Brain* Capsules - Brain Support Supplement with Lion's Mane, Reishi & Cordyceps Mushroom - Herbal Supplement for Memory & Focus Support - 60 Capsules
Host Defense Store
|
$23.96 | 9d | $23.96 | View on Amazon |
| 61 |
VitaUp Mushroom Supplement - USA Made 10 in 1 Mushroom Gummies - Mushroom Complex with Lions Mane, Cordyceps, Turkey Tail, Reishi, Shiitake for Cognitive & Immune Support - 60 Count
VitaUp Store
|
$24.91 | 1d | $24.91 | View on Amazon |
| 62 |
Sugar Free Lions Mane Supplement Gummies with KSM-66 Ashwagandha - Nootropic Supplement for Cognition, Brain Fog, Mental Clarity, Focus & Stress Support - Natural Berry Flavor, Vegan, Made in USA
Purify Life Store
|
$24.95 | 2d | $24.95 | View on Amazon |
| 63 |
Host Defense Mushrooms Lion's Mane - Supplement Capsules for Brain Health Support - Mushroom Support for Focus & Memory Function - Immune & Nervous System Supplement - 60 Capsules
Host Defense Store
|
$25.46 | 30d | $25.46 | View on Amazon |
| 64 |
Gaia Herbs Lion's Mane Mushroom Gummies - Brain Support Supplement* - Made with Organic Lion's Mane Mushrooms - Free from Gluten, Soy & Dairy - 60 Vegan Gummies (30 Servings)
Gaia Herbs Store
|
$26.99 | 12d | $26.99 | View on Amazon |
| 65 |
Nootropics Depot Erinamax Lion's Mane 500mg Capsules | Liquid Culture Mycelium | 2.5mg Erinacine A | Mood, Cognition, & Nerve Support | 120 Count
Nootropics Depot Store
|
$27.50 | 60d | $109.99 | View on Amazon |
| 66 |
NooMost Lions Mane Mushroom Supplement Capsules 1080mg With Ginkgo Biloba - Energy, Focus, Clarity & Memory Support - Real Superfood for Brain Health for Men & Women - Made in USA - 60 Veg Caps
NooMost Store
|
$28.95 | 32d | $28.95 | View on Amazon |
| 67 |
MARYRUTH'S Organics Lions Mane Supplement | Ultra Absorption Liposomal | Full Spectrum Lion's Mane Mushroom | 200mg Beta-Glucans Per Serving | USDA Organic | Vegan | 7.6 oz | 15 Servings
MARYRUTH'S Store
|
$49.90 | 15d | $24.95 | View on Amazon |
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