Calcium alpha-ketoglutarate (Ca-AKG) is a calcium salt of alpha-ketoglutarate, a key intermediate in the Krebs cycle involved in cellular energy production. It gained attention in the longevity space after a 2020 mouse study showed significant lifespan extension and reduced frailty. AKG levels naturally decline with age, and supplementation aims to restore them. Human clinical trials are still in early stages. The "calcium" in Ca-AKG refers to the mineral salt form, not an additional calcium supplement — though it does contribute a small amount of dietary calcium. Products below are ranked by cost at your chosen daily dose.
Read our Ca-AKG (Calcium Alpha-Ketoglutarate) price comparison guide for tips on what to look for when buying ca-akg (calcium alpha-ketoglutarate).
| # | Product | 30-day cost | Supply | Sticker | |
|---|---|---|---|---|---|
| 1 |
Codeage Liposomal Calcium AKG Supplement - Calcium Alpha-Ketoglutarate - 2-Month Supply - Liposomal Delivery - 1 Capsule Per Serving - Non-GMO, Gluten-Free - 60 Capsules
Codeage Store
|
$14.99 | 42d | $29.99 | View on Amazon |
| 2 |
Renue By Science CA AKG Supplement | High Strength Liposomal Calcium AKG | 90 Calcium Alpha-Ketoglutarate Capsules - 300mg CA AKG per Serving CA-AKG Supplement | Non-GMO & Made in The USA
Renue By Science Store
|
$16.32 | 27d | $48.95 | View on Amazon |
| 3 |
Toniiq 1500mg Ultra High Purity Ca AKG Supplement - 99%+ Highly Purified and Bioavailable Calcium Alpha-Ketoglutarate - Calcium AKG Longevity Supplement - 120 Ca-AKG Vegetarian Capsules
Toniiq
|
$16.85 | 60d | $22.47 | View on Amazon |
| 4 |
Liposomal Calcium AKG Supplement 1500 MG (Alpha-Ketoglutaric Acid), More Effective Than AAKG, Ca AKG for Longevity, Age Defense, Cellular Energy, Metabolic Function, 120 Softgels
AJAXERRUE Store
|
$17.50 | 90d | $34.99 | View on Amazon |
| 5 |
Liposomal Calcium AKG Supplement 1500 MG (Alpha-Ketoglutaric Acid), More Effective Than AAKG, Ca AKG for Longevity, Age Defense, Cellular Energy, Metabolic Function, 60 Softgels
AJAXERRUE Store
|
$21.99 | 45d | $21.99 | View on Amazon |
| 6 |
Maxx Herb Calcium AKG, Pure Calcium Alpha - Ketoglutarate Powder (Ca-AKG), for Energy, Vitality, Mental Focus, Clarity & DNA Structure, Non-GMO & Gluten Free - 100 Gram Jar (67 Servings)
Maxx Herb Store
|
$22.37 | 101d | $49.95 | View on Amazon |
| 7 |
2 Pack Liposomal Calcium AKG Supplement 1500mg with Vitamin D3 & K2 for Women & Men, Calcium Supplement with Magnesium Glycinate, Boron, Probiotics & Vitamin C for Bone Strength & Energy, 240 Softgels
Nextdia Store
|
$25.00 | 90d | $49.99 | View on Amazon |
| 8 |
LongJuvity Calcium Alpha-Ketoglutarate Time Release AKG Supplement (1,000mg Per Serving) - Gut Health, Bone Health, Anti Aging & Longevity - Independently Lab Tested (60 Enteric Coated Capsules)
LongJuvity Labs Store
|
$25.95 | 30d | $25.95 | View on Amazon |
Look for Calcium Alpha-Ketoglutarate or Calcium AKG on the Supplement Facts panel. Labels checked for this update showed 300 mg, 700 mg, 1000 mg, and 1500 mg Ca-AKG servings, with serving sizes ranging from 1 capsule to 3 capsules or 1 scoop.
The biggest cost differences come from labeled Ca-AKG per serving, servings per container, and delivery format. Liposomal capsules, time-release capsules, and powder can rank very differently once normalized to the same daily dose.
Do not treat A-AKG, OKG, GKG, or nitric-oxide booster blends as Ca-AKG just because the title contains similar AKG language. Those are different label lines and should not be ranked as Calcium Alpha-Ketoglutarate products.
Ca-AKG remains an emerging-evidence category. The rankings compare the labeled Ca-AKG amount and current price; they do not validate longevity, anti-aging, liposomal, or time-release claims.
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