Ca-AKG (calcium alpha-ketoglutarate) is an AKG supplement bound to calcium. It is most often sold for longevity, healthy aging, cellular energy, and sometimes bone-health positioning. The category is still small, so price differences often come from form, serving size, and marketing claims rather than a huge range of ingredient types.
Human evidence is still limited. Most of the excitement around Ca-AKG comes from animal research and early aging-biology interest, not a large body of long-term human trials. Supplement labels commonly land around 1000-2000 mg/day, so the tables below use 1000 mg/day as a consistent comparison point. That makes capsules, softgels, and powders easier to compare on the same monthly-cost basis.
Prices as of June 3, 2026. Prices update daily; this page updates monthly. For current prices and full interactive filters, see the Ca-AKG (Calcium Alpha-Ketoglutarate) compare page.
| Rank | Brand | Product | Form | Cost per month | Price |
|---|---|---|---|---|---|
| 1 | Toniiq | Toniiq 1500mg Ultra High Purity Ca AKG Supplement - 99%+ Hi… | Capsules | $11.23 | $22.47 |
| 2 | AJAXERRUE | Liposomal Calcium AKG Supplement 1500 MG (Alpha-Ketoglutari… | Softgels | $11.66 | $34.99 |
| 3 | Maxx Herb | Maxx Herb Calcium AKG, Pure Calcium Alpha - Ketoglutarate P… | Powder | $14.91 | $49.95 |
| 4 | Nextdia | 2 Pack Liposomal Calcium AKG Supplement 1500mg with Vitamin… | Softgels | $16.66 | $49.99 |
| 5 | Codeage | Codeage Liposomal Calcium AKG Supplement - Calcium Alpha-Ke… | Capsules | $21.42 | $29.99 |
| 6 | LongJuvity Labs | LongJuvity Calcium Alpha-Ketoglutarate Time Release AKG Sup… | Capsules | $25.95 | $25.95 |
| 7 | Renue By Science | Renue By Science CA AKG Supplement | High Strength Liposom… | Capsules | $54.39 | $48.95 |
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1) Make sure the label says calcium alpha-ketoglutarate. Some product titles use "AKG" loosely. Ca-AKG is not the same thing as AAKG, which is arginine alpha-ketoglutarate and is usually sold in exercise formulas. If you want Ca-AKG, the Supplement Facts panel should name calcium alpha-ketoglutarate, calcium AKG, or Ca-AKG directly.
2) Read the serving size before comparing bottle counts. A product that advertises 1500 mg may require 2 softgels or 3 capsules per serving. A 120-count bottle can last 120 days, 60 days, or 40 days depending on the serving size. The rankings account for both serving amount and servings per container, but the label still tells you how many pills or scoops you would actually take.
3) Do not add the calcium number to the Ca-AKG number. Some labels list the full Ca-AKG amount and also show elemental calcium separately, such as 1500 mg Ca-AKG plus 300 mg calcium. That calcium is part of the Ca-AKG compound, not an extra active amount to add on top. For price comparison, use the labeled Ca-AKG amount.
4) Treat liposomal and blend claims as tie-breakers, not the starting point. Several Ca-AKG products are marketed as liposomal or include extras such as piperine, vitamins, minerals, phosphatidylcholine, or probiotics. Those may matter to some buyers, but they make value harder to judge if your main goal is Ca-AKG. Start with the labeled Ca-AKG amount, serving size, and monthly cost, then decide whether the extras are worth paying for.
5) Pick the form you will actually use. Powders can be cheaper and easier to adjust, but they require measuring. Capsules and softgels are simpler for routine use and travel. If two products are close in monthly cost, clearer labeling and basic quality signals like third-party testing claims or GMP language can help break the tie.
Evidence for Ca-AKG supplementation is emerging. Interest is driven mostly by animal studies and early research around metabolism and aging, while human evidence is still limited. The 1000 mg/day benchmark here is for price comparison, not a claim that 1000 mg/day is the best or most proven dose.
If you're pregnant or breastfeeding, have kidney disease, a history of kidney stones, calcium-related medical issues, or take prescription medications, talk with a clinician before adding Ca-AKG. Because Ca-AKG contains calcium, it may be worth reviewing total calcium intake if you also use calcium supplements or have been advised to limit calcium.