PQQ (Pyrroloquinoline Quinone), ranked by real cost

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PQQ (pyrroloquinoline quinone) is a redox cofactor found in small amounts in foods like kiwi, green peppers, and natto. It is primarily studied for its role in stimulating mitochondrial biogenesis — the creation of new mitochondria — which is unique among commonly available supplements. PQQ also functions as a potent antioxidant, with a stability that allows it to cycle through thousands of oxidation-reduction reactions. Typical supplemental doses range from 10–40mg per day. It is often taken alongside CoQ10 or ubiquinol for synergistic mitochondrial support. PQQ is primarily available in capsule and lozenge form. Products below are ranked by cost at your chosen daily dose.

38 products
# Product 30-day cost Supply Sticker
1
LIIFE Vitamin B12 (Methylcobalamin)+ PQQ 5000 mcg | 180 Chewable Tablets | Supports General Energy, Brain & Nervous System Health | Gluten Free | 1 Capsule per Serving*
LIIFE Store
CapsulesFew reviews
$3.83 45d $22.99 View on Amazon
2
Carlyle PQQ Supplement 20 mg | 60 Capsules | Non-GMO and Gluten Free
Carlyle Store
Capsules
$5.00 60d $9.99 View on Amazon
3
BESTVITE PQQ 20mg (Pyrroloquinoline Quinone) (120 Vegetarian Capsules) - No Stearates - Vegan - Non GMO - Gluten Free
BESTVITE Store
Capsules3rd-party tested
$5.62 120d $22.49 View on Amazon
4
Health Thru Nutrition PQQ 20mg 120 Servings Pyrroloquinoline Quinone as PureQQ | Promotes Mitochondrial Biogenesis | Certified Vegan | Non-GMO Gluten Soy Free Capsules| Clean Label PQQ Supplement
Health Thru Nutrition Store
Capsules
$5.74 120d $22.95 View on Amazon
5
Toniiq 99%+ 20mg Supplement - Ultra High Purity PQQ 20mg Concentrated Formula - PQQ 20 mg 120 Capsules - Pyrroloquinoline Quinone Supplement - 1 Capsule Serving - Vegetarian Capsules
Toniiq
Capsules
$5.90 120d $23.60 View on Amazon
6
MONOHERB PQQ 40 milligrams - PQQ Supplement, Pyrroloquinoline Quinone, 120 Capsules
MONOHERB Store
Capsules
$7.00 240d $27.99 View on Amazon
7
Toniiq 99%+ 40mg Supplement - Ultra High Purity PQQ 40mg Concentrated Formula - PQQ 40 mg 120 Capsules - Pyrroloquinoline Quinone Supplement - 1 Capsule Serving - Vegetarian Capsules
Toniiq
Capsules
$7.49 240d $29.97 View on Amazon
8
Life Extension PQQ Caps – Pyrroloquinoline Quinone, 10 mg – Promotes the Growth of New Mitochondria, ATP, Energy Support – Gluten-Free, Non-GMO, Vegetarian – 60 Capsules
Life Extension Store
Capsules
$7.50 30d $15.00 View on Amazon
9
Nutricost PQQ (Pyrroloquinoline Quinone) 20mg, 60 Capsules | Vegetarian Capsules, GMO-Free, Gluten Free
Nutricost Store
Capsules
$8.97 60d $17.94 View on Amazon
10
Health Thru Nutrition PQQ 20mg 60 Servings Pyrroloquinoline Quinone as PureQQ | Promotes Mitochondrial Biogenesis | Certified Vegan | Non-GMO Gluten Soy Free Capsules| Clean Label PQQ Supplement
Health Thru Nutrition Store
Capsules
$8.99 60d $17.99 View on Amazon
11
Research Labs Ultra High Purity 20mg PQQ Capsules, 120 Capsules. Pure, Concentrated High Bioavailability. Pyrroloquinoline Quinone Supplement ATP Energy, Heart, Cognitive Support Nootropic
Research Labs Store
Capsules
$8.99 60d $17.99 View on Amazon
12
Health Thru Nutrition PQQ 40mg 120 Servings Pyrroloquinoline Quinone as PureQQ | Promotes Mitochondrial Biogenesis | Certified Vegan | Non-GMO Gluten Soy Free Capsules| Clean Label PQQ Supplement
Health Thru Nutrition Store
Capsules
$9.24 240d $36.95 View on Amazon
13
Horbäach PQQ Supplement 40 mg | 120 Capsules | Maximum Strength | Non-GMO and Gluten Free Supplement | Pyrroloquinoline Quinone Disodium Salt
Horbäach Store
Capsules
$9.89 120d $19.79 View on Amazon
14
PQQ Supplement - 20mg, 60 Capsules (Pyrroloquinoline Quinone) Promotes Mitochondria ATP Coenzyme Levels, Energy Optimizer and Sleep Support (Non-GMO, Gluten Free, Vegan Safe) by Double Wood
Double Wood Supplements Store
Capsules
$9.98 60d $19.95 View on Amazon
15
BESTVITE PQQ 40mg (Pyrroloquinoline Quinone) (60 Vegetarian Capsules) - No Stearates - Vegan - Non GMO - Gluten Free
BESTVITE Store
Capsules3rd-party testedFew reviews
$10.40 120d $20.79 View on Amazon
16
Nutricost PQQ (Pyrroloquinoline Quinone) 20mg, 30 Capsules - Vegetarian Capsules, Non-GMO, Gluten Free
Nutricost Store
Capsules
$12.95 30d $12.95 View on Amazon
17
Health Thru Nutrition PQQ 20mg 30 Servings Pyrroloquinoline Quinone as PureQQ | Promotes Mitochondrial Biogenesis | Certified Vegan | Non-GMO Gluten Soy Free Capsules| Clean Label PQQ Supplement
Health Thru Nutrition Store
Capsules
$12.95 30d $12.95 View on Amazon
18
PQQ Supplement 40 MG | High Strength Pyrroloquinoline Quinone for Mitochondrial Biogenesis, Cellular Energy & Brain Health Support | Mitochondria Supplement | Third-Party Tested, Non-GMO | 60 Ct
SMNutrition Store
Capsules3rd-party tested
$12.99 60d $12.99 View on Amazon
19
Swanson Pqq Pyrroloquinoline Quinone 20 mg 30 Veg Caps (2 Pack)
Swanson Ultra
CapsulesFew reviews
$13.19 60d $26.39 View on Amazon
20
PQQ Supplement 20mg - Pyrroloquinoline Quinone, Single Ingredient, Vegan, Gluten Free, No Fillers, Unflavored, 2 Capsules Daily, 60 Capsules (30-Day Supply)
YOUBYNATURE Store
CapsulesFew reviews
$13.49 30d $13.49 View on Amazon
21
Swanson Pqq Pyrroloquinoline Quinone 20 Milligrams 30 Veg Capsules
Swanson Store
Capsules
$13.89 30d $13.89 View on Amazon
22
Health Thru Nutrition PQQ 40mg 30 Servings Pyrroloquinoline Quinone as PureQQ | Promotes Mitochondrial Biogenesis | Certified Vegan | Non-GMO Gluten Soy Free Capsules| Clean Label PQQ Supplement
Health Thru Nutrition Store
Capsules
$13.99 60d $13.99 View on Amazon
23
PQQ Supplement 40mg - Pyrroloquinoline Quinone Veggie Capsules for Cellular Energy Support, Clean Formula, Gluten Free, 60 Capsules, 30 Servings
YOUBYNATURE Store
CapsulesFew reviews
$14.00 60d $14.00 View on Amazon
24
MONOHERB PQQ 20 milligrams - PQQ Supplement, Pyrroloquinoline Quinone, 90 Capsules
MONOHERB Store
Capsules
$15.20 90d $45.60 View on Amazon
25
Source Naturals PQQ Mind, for Neuroprotective Cognitive Support* - 60 Tablets
Source Naturals Store
TabletsFew reviews
$15.23 60d $30.45 View on Amazon
26
BESTVITE PQQ 40mg (Pyrroloquinoline Quinone) (120 Vegetarian Capsules) (60 x 2) - No Stearates - Vegan - Non GMO - Gluten Free
BESTVITE Store
Capsules3rd-party testedFew reviews
$20.24 120d $40.49 View on Amazon
27
Life Extension PQQ, pyrroloquinoline Quinone, 20 mg, Promotes The Growth of New Mitochondria, Gluten-Free, Non-GMO, Vegetarian, 1 Daily, 30 Capsules
Life Extension Store
Capsules
$20.49 30d $20.49 View on Amazon
28
PQQ Supplement 40mg | Pyrroloquinoline Quinone | 60 Veggie Capsules | 30 Servings | Single Ingredient | Clean Formula | Non-GMO
InnerHerb Store
CapsulesFew reviews
$21.00 60d $21.00 View on Amazon
29
Jarrow Formulas® PQQ 20 mg, Dietary Supplement, Heart, Brain, and Metabolism Support, 60 Veggie Capsules, 60 Day Supply
Jarrow Formulas Store
Capsules
$22.47 60d $44.94 View on Amazon
30
Life Extension PQQ (Pyrroloquinoline Quinone) 20 mg, 60 Vegetarian Capsules
Life Extension Store
CapsulesFew reviews
$22.80 60d $45.60 View on Amazon
31
Doctor's Best PQQ with BioPQQ Supplement 20 mg - Brain Health Support for Men & Women, Pyrroloquinoline Quinone Capsules, Daily Mitochondrial Function & Energy Support, Gluten Free, Vegan- 30 Veg Caps
Doctor's BEST Store
Capsules
$24.99 30d $24.99 View on Amazon
32
Life Extension Super Ubiquinol CoQ10 with PQQ, coenzyme Q10, pyrroloquinoline Quinone, Heart Health Supplement, Maximum Absorption, 100 mg, Non-GMO, Gluten-Free, 30 softgels
Life Extension Store
Softgels
$28.30 15d $28.30 View on Amazon
33
Super PQQ Liquid - Highly Absorbable Pyrroloquinoline Quinone 20 Milligram, Best Liquid PQQ for Mitochondrial Biogenesis, Supports Heart Health, Cognitive Function and Mental Focus
MBS Biotechnology Store
Liquid
$30.93 32d $32.99 View on Amazon
34
Life Extension Super Ubiquinol CoQ10 with PQQ, 30 softgels (Pack of 2)
Life Extension Store
Softgels
$31.75 30d $63.50 View on Amazon
35
NaturesPlus Brainceutix PQQ - 60 Vegan Capsules - Supplement for Memory, Clarity & Brain Power - Enhanced Energy, Anti-Aging - Pyrroloquinoline Quinone (PQQ) - Vegetarian, Gluten-Free - 30 Servings
NaturesPlus Store
CapsulesFew reviews
$32.26 30d $32.26 View on Amazon
36
Seeking Health PQQ Lozenge - Support Energy & Healthy Aging with Antioxidant Supplement - 20 mg, 30 Lozenges
Seeking Health Store
Lozenges
$35.00 30d $35.00 View on Amazon
37
Pure Encapsulations Ultra B-Complex with PQQ | Vitamin B Supplement to Support Nerves, Cells, Methylation, and Mitochondrial Health* | 60 Capsules
Pure Encapsulations Store
Capsules
$45.25 30d $90.50 View on Amazon
38
Designs for Health Mitochondria Energy Formula with Bio-PQQ - Mito-PQQ Rhodiola + 20mg PQQ (Pyrroloquinoline Quinone) Supplement - Supports Mitochondrial Biogenesis + Healthy Aging (60 Capsules)
Designs for Health Store
Capsules
$85.99 30d $85.99 View on Amazon
What this PQQ (Pyrroloquinoline Quinone) comparison normalizes

Live table role

This is the current ranking surface for PQQ (Pyrroloquinoline Quinone). It recalculates cost per month from product price, Supplement Facts active amount, servings per container, and the dose you enter above.

Data coverage

42 active products have enough price and label data to calculate cost before display filters; 38 rows are currently shown in the ranked table. The current review floor for this category is 25+ reviews before any large-category and duplicate/bulk filtering.

Price landscape

At 20 mg/day, visible products range from $3.83-$85.99/mo with a $13.34/mo median midpoint and a 22.5x low-to-high spread.

Buying notes for PQQ (Pyrroloquinoline Quinone)

How to read the label

Look for the PQQ amount and whether the label names pyrroloquinoline quinone, PQQ disodium salt, or a branded form. Labels reviewed for this update included standalone capsules and formulas paired with CoQ10, ubiquinol, or other mitochondrial-support ingredients.

What changes the real cost

Because the comparison dose is small, price is driven by bottle count, branded positioning, and whether PQQ is sold alone or inside a more expensive mitochondrial stack. Combo products can be useful, but they blur the PQQ-specific cost.

Common comparison traps

Do not count the whole mitochondrial blend as PQQ. If CoQ10, ubiquinol, or B vitamins are included, compare the listed PQQ amount separately and treat the rest as add-ons.

Evidence context

PQQ has emerging evidence, with mechanistic and animal data around mitochondrial biology and limited human trials. TrueServing compares labeled PQQ cost at 20 mg/day and does not rank energy or cognition claims.

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