Berberine phytosome is a bioavailability-enhanced form of berberine, typically using a phospholipid complex (most commonly Berbevis or similar branded formulations) to improve absorption. Standard berberine HCl has relatively low oral bioavailability, and phytosome technology addresses this by binding berberine to sunflower lecithin. This allows lower doses (typically 500mg/day vs 1500mg/day for HCl) while maintaining comparable blood levels. The lower dosing also tends to reduce the gastrointestinal side effects common with high-dose berberine HCl. Products below are ranked by cost at your chosen daily dose.
Read our Berberine Phytosome price comparison article for tips on what to look for when buying berberine phytosome.
| # | Product | 30-day cost | Supply | Sticker | |
|---|---|---|---|---|---|
| 1 |
Enzymedica Berberine Phytosome High Absorption Supplement - Berbevis Berberine Phytosome Capsules for Men & Women, Bioavailable Formula, Natural Metabolic Health Support, Vegan, Gluten Free - 60 Caps
Enzymedica Store
|
$9.28 | 15d | $18.56 | View on Amazon |
| 2 |
Enzymedica Berberine Phytosome High Absorption Supplement - Berbevis Berberine Phytosome Capsules for Men & Women, Bioavailable Formula, Natural Metabolic Health Support, Vegan, Gluten Free - 60 Caps
Enzymedica Store
|
$9.28 | 15d | $18.56 | View on Amazon |
| 3 |
Prominent Nutrition Berberine Phytosome Supplement, Healthy Gut Support, 550 mg, 60 Count - 2 Pack
Prominent Nutrition Store
|
$12.75 | 60d | $50.99 | View on Amazon |
| 4 |
Berberine Phytosome with Berbevis, 550mg Enhanced Absorption Supplement for Metabolic Support & Heart Health, Highly Bioavailable Berberine Complex, Gluten-Free, Non-GMO, 60 Vegetarian Capsules
Natural BioScience Store
|
$13.32 | 45d | $39.95 | View on Amazon |
| 5 |
Prominent Nutrition Berberine Phytosome - Up to 9.6X Superior Absorption - Standardized Berberine for Digestive, Gut & Heart Health Support - Non-GMO, Vegan & Gluten-Free - 60 Capsules (60 Servings)
Prominent Nutrition Store
|
$13.49 | 30d | $26.99 | View on Amazon |
| 6 |
Ultimate Berberine Phytosome for Optimal Metabolic Health After 40, 9.6X Absorption Dual Action Formula for Appetite & Gut Health, Immunity & Cholesterol Support, Clinical Dose & Third Party Tested
Ultimate Store
|
$14.98 | 30d | $29.95 | View on Amazon |
| 7 |
Feel_Goods_Berberine Phytosome High Absorption Vegan Capsules, 120 Count, Blood Glucose Support, 550mg, 4X Better Absorption
Generic
|
$15.75 | 60d | $62.99 | View on Amazon |
| 8 |
Igennus Dual Action Berberine Phytosome 550mg & Chromium Picolinate, 10x Absorption, Blood Glucose Control, Standardized Berberis Extract Supplement, Clean Label, Vegan, 60 Capsules
Igennus Healthcare Nutrition Store
|
$17.42 | 30d | $34.85 | View on Amazon |
| 9 |
Berberine Supplement 1000mg - Bioavailable Berberine Phytosome Supplement for Metabolism Support & Circulatory Wellness - 7X Absorption - Non-GMO, Gluten-Free – 60 Capsules
PURECRAFT Store
|
$18.56 | 30d | $18.56 | View on Amazon |
| 10 |
B’Leaf Nature Berberine Phytosome, 120 Capsules – 1100mg Berberine Supplement for Metabolic and Cardiovascular Support – Vegan, Gluten-Free, Non-GMO Berberine Phytosome Capsules for Immune Wellness
B'LEAF NATURE Store
|
$18.87 | 60d | $37.74 | View on Amazon |
| 11 |
Berberine Phytosome with Berbevis, 550mg Enhanced Absorption Supplement for Metabolic Support & Heart Health, Highly Bioavailable Berberine Complex, Gluten-Free, Non-GMO, 60 Vegetarian Capsules
Natural BioScience Store
|
$19.97 | 30d | $39.95 | View on Amazon |
| 12 |
Pure Encapsulations Berberine UltraSorb - Enhanced Absorption Berberine Phytosome 550 mg - Supports Metabolic & Cardiometabolic Health* - 60 Capsules
Pure Encapsulations Store
|
$25.75 | 30d | $51.50 | View on Amazon |
| 13 |
Silver Fern Brand Metabolism Supplement + Berberine Phytosome & aXivite – Supports Function & Wellness – 60 Capsules
Silver Fern Store
|
$27.25 | 30d | $54.49 | View on Amazon |
| 14 |
NatureWise Berberine 1000mg - Berberine Phytosome + HCI + Turmeric & Digestive Enzymes - Supports Healthy Blood Sugar + GI + Metabolism + Cholesterol - Non-GMO, USA Manufactured - [30 Day Supply]
NatureWise Store
|
$29.74 | 15d | $29.74 | View on Amazon |
| 15 |
Nature Made Better Absorption Berberine Phytosome Supplement, 1100mg Per 2 Capsules Daily, Berberine Supplement for Cardiovascular Health Support, 60 Capsules, 30 Day Supply
Nature Made Store
|
$33.99 | 30d | $33.99 | View on Amazon |
| 16 |
Theralogix Berberine Enhanced Absorption - 30-Day Supply - Made with Berberine Phytosome to Help Support Healthy Metabolism & Hormone Balance* - NSF Certified - 30 Capsules
Theralogix Store
|
$36.75 | 15d | $36.75 | View on Amazon |
This is the current ranking surface for Berberine Phytosome. It recalculates cost per month from product price, Supplement Facts active amount, servings per container, and the dose you enter above.
22 active products have enough price and label data to calculate cost before display filters; 16 rows are currently shown in the ranked table. The current review floor for this category is 25+ reviews before any large-category and duplicate/bulk filtering.
At 1100 mg/day, visible products range from $9.28-$36.75/mo with a $17.99/mo median midpoint and a 4.0x low-to-high spread.
Confirm the label is a berberine phytosome product and read the berberine-phytosome amount directly. Labels reviewed for this update included branded phytosome-style capsules and metabolic blends where berberine may be paired with chromium, cinnamon, or other ingredients.
Phytosome positioning, branded material, serving count, and combo-formula add-ons drive cost. These products should not be priced directly against ordinary berberine HCl without recognizing the different form and evidence base.
Do not count a metabolic blend as berberine phytosome unless the active line is broken out. Also avoid assuming a phytosome dose is equivalent to a berberine HCl dose; TrueServing compares the labeled phytosome-category amount.
Berberine phytosome has moderate evidence with improved-absorption rationale but fewer independent studies than berberine HCl. TrueServing compares labeled berberine phytosome cost at 1,100 mg/day.
TrueServing participates in the Amazon Associates program. We may earn a commission when you purchase through our links at no extra cost to you. Prices are updated regularly but may vary.